BD-1, beta-Defensin 1 (47a.a), human

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BD-1, beta-Defensin 1 (47a.a), human

Cat.#: RC220-12

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DG: No

Storage: (-15 to -20)C

Sterile: Yes

Stock: Inquire

US$64.43

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US$64.43

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Product Description: BD-1, beta-Defensin 1 (47a.a), human: Defensins (alpha and beta) are cationic peptides with a broad spectrum of antimicrobial activity that comprise an important arm of the innate immune system. The α-defensins are distinguished from the β-defensins by the pairing of their three disulfide bonds. To date, four human β-defensins have been identified; BD-1, BD-2, BD-3 and BD-4. β-defensins are expressed on some leukocytes and at epithelial surfaces. In addition to their direct antimicrobial activities, they are chemoattractant towards immature dendritic cells and memory T cells. The β-defensin proteins are expressed as the C-terminal portion of precursors and are released by proteolytic cleavage of a signal sequence and, in the case of BD-1 (36 a.a.), a propeptide region. β-defensins contain a six-cysteine motif that forms three intra-molecular disulfide bonds. β-Defensins are 3-5 kDa peptides ranging in size from 33-47 amino acid residues., UnitProt ID: P60022

Number of Containers: 1

Refrigeration Requirements: Freezer

Shipping Conditions: ICE

UNSPSC Code: 12352202

UNSPSC Category: Other Enzymes

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