NOGGIN | Bio Basic

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NOGGIN, human

Cat.#: RC219-20

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Size:
RC219-20 (5ug)
RC219-20 (20ug)
RC219-20 (1mg)

Quantity:

DG: No

Storage: (-15 to -20)C

Sterile: Yes

Stock: Inquire

US$64.43

*size

US$64.43

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Product Description: NOGGIN, human: Noggin belongs to a group of diffusible proteins which bind to ligands of the TGF-β family and regulate their activity by inhibiting their access to signaling receptors. Noggin was originally identified as a BMP-4 antagonist whose action is critical for proper formation of the head and other dorsal structures. Consequently, Noggin has been shown to modulate the activities of other BMPs including BMP-2,-7,-13, and -14. Targeted deletion of Noggin in mice results in prenatal death and recessive phenotype displaying a severely malformed skeletal system. Conversely, transgenic mice over-expressing Noggin in mature osteoblasts display impaired osteoblastic differentiation, reduced bone formation, and severe osteoporosis., UnitProt ID: Q13253

Total Product Size:
RC219-20 (5ug)
RC219-20 (20ug)
RC219-20 (1mg)

Number of Containers: 1

Refrigeration Requirements: Freezer

Shipping Conditions: ICE

UNSPSC Code: 41116127

UNSPSC Category: Other Cytokines and Chemokines

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