MIP-5, CCL15, human

Product Description: MIP-5, CCL15, human: CCL15, a new human CC chemokine, was isolated from a human fetal spleen cDNA library. CCL15 cDNA encodes a predicted 113 amino acid (aa) protein containing a putative signal peptide of 21 amino acids that is cleaved to generate a 92 aa residue mature protein. Within the CC family members, human CCL15 shares 45%, 44%, 35%, and 30% aa homology with mouse C10, human MPIF-1, human HCC-1, and mouse MIP-1γ, respectively. The gene for MIP-5 is found on chromosome 17 where the genes for most of the human CC chemokines are located. Human CCL15 is expressed in T and B lymphocytes, NK cells, monocytes and monocyte-derived dendritic cells. Human MIP-5 is chemotactic for T cells and monocytes and has been shown to induce calcium flux in human CCR-1-transfected cells., UnitProt ID: Q16663

Number of Containers: 1

Refrigeration Requirements: Freezer

Shipping Conditions: ICE

UNSPSC Code: 41116127

UNSPSC Category: Other Cytokines and Chemokines

MIP-5, CCL15, human

Cat.#: RC315-26

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